Class II

IV Dose
Oral doseDrug of choice in vasodepressor syncope, because of intrinsic sympathomimetic activity. 10-60 mg/day in adults divided bid
KineticsPlasma half-life 3-4 hours. Clearance reduced in uremia
CautionsSimilar to other beta blockers.
InteractionsISA may be blocked by other beta blockers
PreparationsVisken “heart-shaped” non-scored tabs: 5, 10 mg.
FDA approval in childrenno