Nadolol

Class II

IV Dose
Oral dose1-2 mg/kg/day, given QD. Adjust up or down after 5 days based on side effects, sinus rate, and efficacy.
LevelsNot yet clinically useful
KineticsElimination half-life 12-24 hours. Peak levels at 3-4 hours after oral dose.
CautionsSimilar to propranolol. Not particularly cardioselective, but fewer CNS side effects.
Interactions
PreparationsCorgard non-scored tabs: 20, 40, 80 mg scored tablets: 120, 160 mg
FDA approval in childrenno
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