Midodrine
Other
IV Dose | No IV form |
Oral dose | Adults: 10 mg TID recommended, 3rd dose not later than 6 pm. |
Levels | unknown |
Kinetics | Direct effect of metabolite on alpha receptors. Peak levels of metabolite at 1-2 hours, half-life of 3-4 hours. |
Cautions | Supine and/or sitting hypertension should be checked for after initiation of therapy. Symptoms may include heart pounding, headache, blurred vision. |
Interactions | May potentiate vagal bradycardia with digoxin. Avoid other vasoconstrictors (e.g. phenylephrine, phenylpropanolamine, dihydroergotamine) Effects antagonized by prazosin) |
Preparations | ProAmatine scored tablets, 2.5, 5 mg |
FDA approval in children | no |